The best material for a dog toy depends on several factors such as the dog's size, age, and chewing habits, as well as the purpose of the toy. Here are some common materials used for dog toys and their pros and cons:

Rubber: Rubber is a popular material for dog toys because it is durable and can withstand a lot of chewing. It also has some bounce to it, making it a good choice for interactive play. However, some dogs may be able to chew through rubber toys and ingest small pieces, which can be a choking hazard.

Rope: Rope toys are great for interactive play and chewing, and they can also help clean a dog's teeth. However, some dogs may chew through the rope and ingest small pieces, which can be a choking hazard.

Nylon: Nylon is a durable material that can withstand heavy chewing. It's also easy to clean and can be used for interactive play. However, some dogs may be able to chew through nylon toys and ingest small pieces, which can be a choking hazard.

Plush: Plush toys are soft and cuddly, making them great for comfort and play. However, they are not as durable as other materials and can be easily destroyed by dogs that like to chew.

Hard plastic: Hard plastic toys are durable and can withstand heavy chewing. They are also easy to clean and can be used for interactive play. However, some dogs may be able to chew through hard plastic toys and ingest small pieces, which can be a choking hazard.

It's important to choose a toy that is appropriate for your dog's size, age, and chewing habits, and to always supervise your dog during playtime to prevent choking hazards.